The COVID-19 pandemic and associated disruptions have had a major impact on the US academic research enterprise. This report provides a landscape review of what is known about these impacts, from March through mid-October 2020, with an aim of identifying gaps that should be addressed. Our focus is on externally funded research, and therefore we emphasize STEM fields almost exclusively. As a result, we also focus on the largest research universities, which conduct an outsized share of this research and which are themselves quite reliant on the intellectual activity and revenues associated with it.